Category: BrainCrit 2024 – Virtual Poster

Working memory is the process through which information is held in mind temporarily. To achieve this neural representations of the data must persist while the information is being held in mind. However, these representations cannot be held in mind indefinitely. Instead, they must be flexible enough to switch between different pieces of information. Here we … Continue reading Poster 2024#5 – Jacob Barfield – Working memory and flexibility are balanced near criticality

The critical brain hypothesis posits that neural systems operate near a critical phase transition, potentially optimizing computation and information processing. However, the precise relationship between criticality and performance in living systems remains a mystery. In this companion study to "Neuronal Scaling in the Mouse Visual Cortex During a Visual Recognition Task," we extend our investigation … Continue reading Poster 2024#4 – Gustavo Gama Cambrainha – With or without scaling? Exploring criticality across brain areas during task performance

The brain is tuned to operate near a critical phase transition between disordered and ordered states by control parameters such as the balance between functionally excitatory and inhibitory neurotransmission. Deviations from this balance are linked to multiple brain disorders making the emergent dynamics a potential mechanistic biomarker. Indeed, neurophysiological biomarkers appear promising for applications in … Continue reading Poster 2024#3 – Alina Suleimanova – Phenotype discovery using personalized generative whole-brain modeling

Whole-brain computational modeling has become increasingly important for understanding the systems-level mechanisms governing the dynamics of large-scale brain activity. Brain dynamics, characterized by synchronization and criticality of neuronal oscillations, are fundamental to cognitive functions. The remarkable inter-individual variability in observables neuronal synchronization dynamics in vivo has been attributed to both individual operating point locations in … Continue reading Poster 2024#2 – Vladislav Myrov – Hierarchical whole-brain modeling of critical synchronization dynamics in human brain

In the brain, synchronous activity is detected as oscillations at different frequencies. Experimental data from the hippocampus and neocortex link Phase-Amplitude Cross Frequency Coupling (PAC), where the amplitude of fast gamma oscillations aligns with the phase of slower theta/alpha waves, to cognitive functions like attention, learning and navigation. Traditionally, this mechanism was thought to be … Continue reading Poster 2024#1 – Dimitrios Chalkiadakis – The connectivity of minimal neuronal motifs could explain gamma-leading theta interactions in recordings of synchronous neural activity